Bobzilla

http://bobzilla.keenspace.com/

Really similar to one of the Comics by Mike Leffel and Bob Scott, Eagle-DNA, so if you like that, check out this one – it's another sporadically updated comic strip in basically the same style; it's the UK Eagle-DNA, but just as good. A bit more non-sequitury/absurdist than Eagle-DNA is, actually, which is something you wouldn't necessarily think was possible. Also, the second comic I know (first is Overcompensating by WIGU creator Jeffrey Rowland) to feature Andrew W. K. as a character.